منابع مشابه
Synaptic cell adhesion.
Chemical synapses are asymmetric intercellular junctions that mediate synaptic transmission. Synaptic junctions are organized by trans-synaptic cell adhesion molecules bridging the synaptic cleft. Synaptic cell adhesion molecules not only connect pre- and postsynaptic compartments, but also mediate trans-synaptic recognition and signaling processes that are essential for the establishment, spec...
متن کاملThe spermatogenic Ig superfamily/synaptic cell adhesion molecule mast-cell adhesion molecule promotes interaction with nerves.
Nerve-mast cell interaction is involved in both homeostatic and pathologic regulations. The molecules that sustain this association have not been identified. Because synaptic cell adhesion molecule (SynCAM), alternatively named spermatogenic Ig superfamily (SgIGSF), is expressed on both nerves and mast cells and because it binds homophilically, this molecule may be a candidate. To examine this ...
متن کاملSynaptic adhesion molecules
Synopsis The chemical synapse is a specialized asymmetric adhesion site between the axon of a neuron and its target cell. Synapse formation is a multi-step process involving target recognition followed by reciprocal inductive interactions that result in recruitment of proteins, such as receptors, and organelles, such as synaptic vesicles, to both the presynaptic and postsynaptic compartments. S...
متن کاملSynaptic adhesion molecules and excitatory synaptic transmission
Synaptic adhesion molecules have been extensively studied for their contribution to the regulation of synapse development through trans-synaptic adhesions. However, accumulating evidence increasingly indicates that synaptic adhesion molecules are also involved in the regulation of excitatory synaptic transmission and plasticity, often through direct or close associations with excitatory neurotr...
متن کاملIntroduction: Cell adhesion and extracellular matrix molecules in synaptic plasticity
This issue of Neuron Glia Biology contains a special collection of original research papers and reviews on the role of cell adhesion and extracellular matrix (ECM) molecules in synaptic plasticity. These molecules are crucially required for building and maintaining synaptic structure during brain development and there is increasing evidence that they also play important roles in modulating dist...
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ژورنال
عنوان ژورنال: Cold Spring Harbor Perspectives in Biology
سال: 2012
ISSN: 1943-0264
DOI: 10.1101/cshperspect.a005694